I am interested in the role of epigenetics in fitness, plasticity, and adaptation processes in wild vertebrates in changing environments. Through molecular biology tools and eco-evolutionary approaches, I aim to understand how wild vertebrates store and inherit environmental exposures and experiences. The goal is to understand fundamental mechanisms of biology, and to develop applications as markers for disease, environmental change or pollution.

Currently, I am involved in the following research projects: 

Recent papers from these projects are:

Ord et al, 2023 on the genetics of epigenetics in adapting stickleback populations
Rieder et al, 2023 on method choices in aquaculture microbiome sequencing approaches
Rieder et al, 2022 on the development of pre-pipetted, dried qPCR mixes for long-term storage and reconstitution



  • Modul 1-3, Morphologische Grundlagen: Vergleichende Morphologie und Systematik (Einführung: Phylogenie und Systematik)
  • Modul 1-8, Digitalisierung: Wildlife Tracking
  • Modul 1-8, Nachhaltigkeit: Sustainable Development
  • Modul 2, Parakliniktage: Schnuppertag im Forschungslabor

Humanmedizin: SJ1-TB6, Nachhaltigkeit

High nucleotide diversity accompanies differential DNA methylation in naturally diverging populations. Ord J, Gossmann TI, Adrian-Kalchhauser I. Molecular Biology and Evolution 40(4), 2023. 

Metagenomics and metabarcoding experimental choices and their impact on microbial community characterization in freshwater recirculating aquaculture systems. Rieder J, Kapopoulou A, Bank C, Adrian-Kalchhauser I. Environmental Microbiome 18, 8 (2023).

Detecting aquatic pathogens with field-compatible dried qPCR assays. Rieder J, Martin-Sanchez PM, Osman OA, Adrian-Kalchhauser I, Eiler A. Journal of microbiological methods 202, 2022.

Inherited Gene Regulation Unifies Molecular Approaches to Nongenetic Inheritance: Response to Edelaar et al. Adrian-Kalchhauser I, Sultan SE, Shama L, Spence-Jones H, Tiso S, Keller Valsecchi CI, Weissing FJ. Trends in Ecology and Evolution. 36(6), 2021. 

Predation on native fish eggs by invasive round goby revealed by species-specific gut content DNA analyses. Lutz E, Hirsch PE, Bussmann K, Wiegleb J, Jermann HP, Muller R, Burkhardt-Holm P, Adrian-Kalchhauser I. Aquatic Conservation 30(8) 2020.

Understanding 'Non-genetic' inheritance: Insights from Molecular-Evolutionary Crosstalk. Adrian-Kalchhauser I, Sultan SE, Shama L, Spence-Jones H, Tiso S, Keller Valsecchi CI, Weissing FJ. Trends in Ecology and Evolution. 35(12) 2020.

The round goby genome provides insights into mechanisms that may facilitate biological invasions. Adrian-Kalchhauser I, blomberg A, Larsson T, Musilova Z, Peart CR, Pippel M, Hongroe Solbakken M, Suurväli J, Walser JC, Wilson JY, Alm Rosenblad M, Burguera D, Gutnik S, Michiels N, Töpel M, Pankov K, Schloissnig S, Winkler S. BMC Biology 2020.

DNA methylation patterns in the round goby hypothalamus support an on-the-spot decision scenario for territorial behaviour. Somerville V, Schwaiger S, Hirsch PE, Walser JC, Bussmann K, Weyrich A, Burkhardt-Holm P, Adrian-Kalchhauser, I. Genes 2019.

Fishing for profit or food? Socio-economic drivers and fishers’ attitudes towards sharks in Fiji. Glaus KBJ, Adrian-Kalchhauser I, Piovano S, Appleyard SA, Brunnschweiler JM, Rico C. Marine Policy 2018.

Long-read sequencing of Benthophilinae mitochondrial genomes reveals the origins of round goby mitogenome re-arrangements. Gutnik S, Walser JC, Adrian-Kalchhauser I. Mitochondrial DNA Part B, 2018. doi: 10.1080/23802359.2018.1547133

RNA sequencing of early round goby embryos reveals that maternal experiences can shape the maternal RNA contribution in a wild vertebrate. Adrian-Kalchhauser I, Walser JC, Schwaiger M, Burkhardt-Holm P. BMC Evolutionary Biology, 2018. 

Colonizing islands of water on dry land – on the passive dispersal of fish eggs by birds. Hirsch P, N’Guyen A, Muller R, Adrian-Kalchhauser I, Burkhardt-Holm P. Fish and Fisheries 2018.

A dynamical model for invasive round goby populations reveals efficient and effective management options. N’Guyen A, Hirsch PE, Bozzuto C, Adrian-Kalchhauser I, Horkova K, Burkhardt-Holm P. Journal of Applied Ecology 2018;55:342–352.

The invasive round goby may attach its eggs to ships of boats – but there is no evidence. Adrian-Kalchhauser I, N’Guyen A, Hirsch PE, Burkhardt-Holm P. Aquatic Invasions 2017, 12(2):263-267

The mitochondrial genome sequences of the round and the sand goby reveal patterns of recent evolution in gobiid fish. Adrian-Kalchhauser I, Svensson O, Kutschera VE, Alm Rosenblad M, Pippel M, Winkler S, Schloissnig S, Blomberg A, Burkhardt-Holm P. BMC Genomics 2017, 18:177

Increased Notch signaling antagonizes PRC2-mediated silencing to promote reprograming of germ cells into neurons. Seelk S*, Adrian-Kalchhauser I*, Hargitai B, Hajduskova M, Gutnik S, Tursun B, Ciosk R. eLife 2016;10.7554/eLife.15477

The invasive bighead goby Ponticola kessleri displays small scale genetic differentiation and large scale genetic homogeneity in relation with shipping patterns. Adrian-Kalchhauser I, Hirsch PE, Behrmann-Godel J, N’Guyen A, Watzlawczyk S, Gertzen S, Borcherding J, Burkhardt-Holm P. Molecular Ecology. 2016 May, 25(9):1925-43

An eDNA Assay to Monitor a Globally Invasive Fish Species from Flowing Freshwater. Adrian-Kalchhauser I, Burkhardt-Holm P. PLOS ONE. 2016 Jan 27; 11 (1):e0147558

A tough egg to crack: recreational boats as vectors for invasive goby eggs and transdisciplinary management approaches. Hirsch PE, Adrian-Kalchhauser I, Flämig S, N’Guyen A, Defila R, Di Giulio A, Burkhardt-Holm P. Ecology and Evolution. 2016 Jan 11; 6(3):707-15

What do we really know about the impacts of one of the 100 worst invaders in Europe? A reality-check. Hirsch PE, N’Guyen A, Adrian-Kalchhauser I, Burkhardt-Holm P. Ambio. 2016 Apr; 45(3):267-79

Improving invasive species management by integrating priorities and contributions of scientists and decision makers. N’Guyen A, Hirsch PE, Adrian-Kalchhauser I, Burkhardt-Holm P. Ambio. 2016 Apr; 45(3):280-9

Characteristics of the shark fisheries of Fiji. Glaus K*, Adrian-Kalchhauser I*, Burkhardt-Holm P, White W, Brunnschweiler J. Nature Scientific Reports. 2015 Dec 2; 5:17556

The complete mitochondrial genome of the invasive Ponto-Caspian goby Ponticola kessleri obtained from high-throughput sequencing using the Ion Torrent Personal Genome Machine. Kalchhauser I*, Kutschera V*, Burkhardt-Holm P. Mitochondrial DNA. 2014 Oct 20:1-3

Arrival of round goby Neogobius melanostomus (Pallas, 1814) and bighead goby Ponticola kessleri (Günther, 1861) in the High Rhine (Switzerland). Kalchhauser I, Mutzner P, Hirsch PE, Burkhardt-Holm P. Biological Invasion Records. 2013; 2(1):79-83

FBF represses the Cip/Kip cell-cycle inhibitor CKI-2 to promote self-renewal of germline stem cells in C. elegans. Kalchhauser I, Farley BM, Pauli S, Ryder SP, Ciosk R. EMBO Journal. 2011 Aug 5; 30(18):3823-9

Translational repression of cyclin E prevents precocious mitosis and embryonic gene activation during C. elegans meiosis. Biedermann B, Wright J, Senften M, Kalchhauser I, Sarathy G, Lee MH, Ciosk R. Developmental Cell. 2009 Sep; 17(3):355-64.

High-resolution, high-throughput SNP mapping in Drosophila melanogaster. Chen D, Ahlford A, Schnorrer F, Kalchhauser I, Fellner M, Viràgh E, Kiss I, Syvänen AC, Dickson BJ. Nature Methods. 2008 Apr; 5(4):323-9.

The transmembrane protein Kon-tiki couples to Dgrip to mediate myotube targeting in Drosophila. Schnorrer F, Kalchhauser I, Dickson BJ. Developmental Cell. 2007 May; 12(5):751-66.