Whether or not we catch the cold that's going around depends on many factors. Early life experiences, and potentially even parental experiences, are a contributing factor. We use the brown trout and its parasite Tetracapsuloides bryosalmonae as model to study the impact of rearing environment on disease severity from the molecular to the macroscopic level.
Specifically, we...
- characterize of brown trout cellular immunity using FACS and single cell RNA sequencing (scRNA seq).
- describe the cellular immune reaction of brown trout to Tetracapsuloides bryosalmonae using infection experiments, qPCR, histology, FACS and scRNA seq.
- determine the impact of rearing environment on the immune response.
- explore immune priming effects in unexposed offspring generations.
This project is supported by a project grant from SNSF awarded to I. Adrian-Kalchhauser.
Project team
Heike Schmidt-Posthaus, Helena Saura Martinez, James Ord, Dragan Stajic, Quinn Coxon, Nicolas Diserens, Irene Adrian-Kalchhauser
Collaborators
Stephanie Talker (IVI, Uni Bern), Monica Hongroe Solbakken (Oslo University)
